2024-03-28T07:59:30Z
http://eyereports.org/index.php/eyereports/oai
oai:eyereports.org:article/37
2014-03-08T11:38:46Z
eyereports:BR
nmb a2200000Iu 4500
"120123 2012 eng "
2039-4756
2039-4748
10.16964/er.v2i1.37
doi
dc
Rhabdomyosarcoma mimicking lymphangioma: report of three cases
Guerriero, Silvana
Department of Ophthalmology, University
of Bari
Ciracì, Lorenza
Department of Ophthalmology, University
of Bari
Giancipoli, Ermete
Department of Ophthalmology, University
of Bari
Fiore, Maria Grazia
Department of Pathology, University of Bari
Piscitelli, Domenico
Department of Pathology, University of Bari
We report three cases of proptosis, in children aged 6, 10 and 12, whereby in all cases the first clinical, radiologic and ultrasonographic diagnosis was lymphangioma, while the final anatomopathological diagnosis was rhabdomyosarcoma. In presence of a rapidly worsening exophthalmos or eyelid swelling in a child, an early correct diagnosis is very important. Imaging techniques play a very important role in the diagnosis, but are often inconclusive and an excisional biopsy (if feasible) must always be considered
Ophthoscience Publishers, Baltimore, Maryland, USA
2012-01-23 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2012.e1
Eye Reports; Vol. 2 No. 1 (2012)
eng
Copyright (c)
oai:eyereports.org:article/38
2014-03-08T11:38:46Z
eyereports:CASE
nmb a2200000Iu 4500
"120131 2012 eng "
2039-4756
2039-4748
10.16964/er.v2i1.38
doi
dc
Late onset post-LASIK keratectasia with reversal and stabilization after use of latanoprost and corneal collagen cross-linking
Stojanovic, Aleksandar
Eye Department, University Hospital of North Norway, Tromsø; SynsLaser Kirurgi AS, Tromsø/Oslo
Chen, Xiangjun
SynsLaser Kirurgi AS, Tromsø/Oslo
Zheng, Linyan
School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical College, Wenzhou, Zhejiang
Xu, Yile
School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical College, Wenzhou, Zhejiang
Stojanovic, Filip
SynsLaser Kirurgi AS, Tromsø/Oslo
Utheim, Tor Paaske
SynsLaser Kirurgi AS, Tromsø/Oslo
We report a case of late onset keratectasia after laser in situ keratomileusis (LASIK) and its quick reversal and stabilization after use of latanoprost and riboflavin/ultraviolet-A corneal collagen cross-linking (CXL). A 39-year-old man with normal intraocular pressure developed a rapid deterioration of vision in his left eye 6 years after LASIK-retreatment for high myopic astigmatism. Keratectasia was diagnosed by corneal topography and ultrasound pachymetry. After two months of treatment with latanoprost and a minor intraocular pressure reduction, uncorrected distance visual acuity improved from 20/100 to 20/20 and corneal topography showed reversal of keratectasia. CXL was performed after the reversal to achieve long-term stabilization. At 1, 3, 6, 13 and 39 months followup exams after the CXL, stable vision, refraction, and topography were registered. This case shows that keratectasia may rapidly occur several years after LASIK and that a quick reversal and stabilization may be achieved by use of latanoprost followed by CXL.
Ophthoscience Publishers, Baltimore, Maryland, USA
2012-01-23 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2012.e2
Eye Reports; Vol. 2 No. 1 (2012)
eng
Copyright (c)
oai:eyereports.org:article/39
2014-03-08T11:38:46Z
eyereports:CASE
nmb a2200000Iu 4500
"120214 2012 eng "
2039-4756
2039-4748
10.16964/er.v2i1.39
doi
dc
Orbital metastatic primary mediastinal neuroendocrine tumor: a histopathological case report
Alkatan, Hind
Pathology and Laboratory Medicine Department, King Khaled Eye specialist Hospital, Riyadh
Ayoubi, Ayman
Oculoplastic and Orbit Division, King Khaled Eye specialist Hospital, Riyadh
Neuroendocrine tumors most frequently involve the gastrointestinal tract and bronchopulmonary system. Few cases of presumed primary neuroendocrine tumors in the orbit have been reported so far and most of the orbital cases are actually metastatic. We describe the unusual occurrence of this tumor in the orbit of a 16-year-old boy. The lesion was initially thought to be primary; however, the diagnosis of a metastatic orbital lesion was later supported by the histopathological appearance of his orbital biopsy, characteristic immunohistochemical profile and the presence of a primary mediastinal tumor. The patient did not have any symptoms suggestive of a carcinoid syndrome during the course of his disease. Unfortunately, tests showed lymph node involvement and distant metastatic lesions and he died from these a few months later while on palliative therapy.
Ophthoscience Publishers, Baltimore, Maryland, USA
2012-01-23 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2012.e3
Eye Reports; Vol. 2 No. 1 (2012)
eng
Copyright (c)
oai:eyereports.org:article/40
2014-03-08T11:38:46Z
eyereports:CASE
nmb a2200000Iu 4500
"120625 2012 eng "
2039-4756
2039-4748
10.16964/er.v2i1.40
doi
dc
Orbital metastasis from cutaneous melanoma
Tsierkezou, Loukia
Birmingham Midland Eye Centre, City Hospital, Birmingham
Cikatricis, Peter
Birmingham Midland Eye Centre, City Hospital, Birmingham
Abdullah, Parveen
Birmingham Midland Eye Centre, City Hospital, Birmingham
Elsherbiny, Samer
Birmingham Midland Eye Centre, City Hospital, Birmingham
We report a case of a metastatic cutaneous melanoma to the orbit. A 60-year-old Caucasian male presented with a 2-day history of left-sided ocular pain, lid swelling and chemosis. Initially, this was treated as conjunctivitis with no signs of improvement. Four days later, the patient developed left proptosis, mechanical ptosis, left esotropia and diplopia. Computed tomography scan of the orbit demonstrated marked thickening of the lateral rectus muscle. The patient was treated as pseudotumor. Subsequent biopsy revealed malignant cutaneous melanoma. The patient had a history of cutaneous melanoma excised 15 years previously. Further imaging showed advanced metastatic disease in the brain, the lung and the liver. The patient passed away five months after initial presentation. Cutaneous melanoma metastasizing to the orbit has poor prognosis. Patients often have advanced disease at the time of presentation and orbital metastases may be the initial sign. A detailed history is paramount in making timely diagnosis.
Ophthoscience Publishers, Baltimore, Maryland, USA
2012-01-23 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2012.e4
Eye Reports; Vol. 2 No. 1 (2012)
eng
Copyright (c)
oai:eyereports.org:article/41
2014-03-08T11:34:14Z
eyereports:ORIG
nmb a2200000Iu 4500
"110706 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.41
doi
dc
Outcomes of 23-gauge pars plana vitrectomy in combined scleral buckling and vitrectomy for complex rhegmatogenous retinal detachments
Schoenberger, Scott D.
Department of Ophthalmology, University of Cincinnati, Ohio
Miller, Daniel M.
Department of Ophthalmology, University of Cincinnati; Cincinnati Eye Institute, Cincinnati, Ohio
Riemann, Christopher D.
Department of Ophthalmology, University of Cincinnati; Cincinnati Eye Institute, Cincinnati, Ohio
Foster, Robert E.
Cincinnati Eye Institute, Cincinnati, Ohio
Petersen, Michael R.
Cincinnati Eye Institute, Cincinnati, Ohio
Rhegmatogenous retinal detachments associated with proliferative vitreoretinopathy, giant retinal tears, ocular trauma, proliferative diabetic retinopathy, or necrotizing retinitis are considered more complex than those without these factors. The aim of the current review is to address the surgical outcomes and complications of 23-gauge pars plana vitrectomy with scleral buckling (23GPPV/SB) for repair of these complex retinal detachments. This retrospective study involved 54 eyes of 53 patients who underwent 23GPPV/SB between July 2007 and September 2009. Preoperative diagnosis, surgical technique, preoperative and postoperative visual acuities, intraoperative and postoperative complications, and anatomic reattachment rates were examined. Fifty-four eyes of 53 patients were reviewed in this study and indications for surgery varied. Mean logarithm of the minimal angle of resolution (logMAR) pre- and post-operative visual acuities were 1.166 (20/293) and 0.780 (20/120), respectively, which led to a statistically significant improvement in logMAR (P=0.0165). Single operation and final reattachment rates were 87% (47 of 54 eyes) and 100%, respectively. Postoperative complications included choroidal effusion/hemorrhage (14.8%, 8 of 54 eyes) and vitreous hemorrhage (11.1%, 6 of 54 eyes). Other more infrequent complications included hyphema (9.3%, 5 of 54 eyes), hypotony (5.6%, 3 of 54 eyes) and ocular hypertension > 35 mmHg (3.7%, 2 of 54 eyes). A total of 31.5% (17 of 54 eyes) of patients had a complication in the postoperative time period, but 58.8% of these resolved spontaneously without requiring an intervention. 23GPPV/SB may be considered for complex retinal detachment repair with good anatomic reattachment rates, but with relatively high complication rates.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e3
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/42
2014-03-08T11:34:14Z
eyereports:ORIG
nmb a2200000Iu 4500
"110802 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.42
doi
dc
What are the half-lives of ranibizumab and aflibercept (VEGF Trap-eye) in human eyes? Calculations with a mathematical model
Stewart, Michael W.
Mayo Clinic School of Medicine, Jacksonville, FL
The aim of the article is to estimate the intravitreal half-lives of ranibizumab and aflibercept (VEGF Trap-eye; VTE) in human eyes. Using a published mathematical model for rabbits, the intravitreal half-lives of ranibizumab and bevacizumab were calculated and compared to empirical data. The slope coefficient within the model was changed to set the bevacizumab output equal to experimental values to meet 3 goals: firstly, to validate the model in rabbit eyes; secondly, to test the mutability of the model to monkey eyes; thirdly, to calculate the half-lives of ranibizumab and the VTE in human eyes. The half-life calculations for ranibizumab deviate from published rabbit and monkey values by only 8.3% and 4.2%. Using the experimentally determined half-life of bevacizumab in human eyes (8.25 days) to set the equation, the half-lives of ranibizumab and the VTE are calculated to be 4.75 days and 7.13 days in human eyes. The intraocular half-lives of ranibizumab and the VTE are estimated using existing published animal and human data and a mathematical model. The validity of these half-lives and binding activities, however, awaits clinical correlation.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e5
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/43
2014-03-08T11:34:14Z
eyereports:ORIG
nmb a2200000Iu 4500
"110812 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.43
doi
dc
Spontaneous ipsilateral subconjunctival hemorrhage and the related risk factors
Kanonidou, Evgenia
Department of Ophthalmology, General Hospital of Veria, Veria
Konidaris, Vasileios
Department of Ophthalmology, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki
Kanonidou, Christina
Postgraduate Student, Aristotle University of Thessaloniki, Thessaloniki
Ziakas, Nikolas
Department of Ophthalmology, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki
The aim of the report is to assess the risk factors among patients with spontaneous ipsilateral subconjunctival hemorrhage (SCH) who presented to the outpatients’ department in General Hospital of Veria, Veria, Greece. Thirty-five patients with SCH participated in the study. A thorough case history was taken and a full ophthalmic examination was performed to identify the risk factors related to the clinical finding. The common hematological parameters associated with the coagulation profile of each patient were evaluated. With the exception of SCH, the ophthalmic examination was normal in all patients. Identified risk factors include history of systemic hypertension (21 patients [60%], mean systolic value: 170 mmHg±15 mmHg), strenuous exercise [19 patients (54%)] and minor ocular trauma [5 patients (14%)]. Other risk factors [each in 2 patients (6%)] included: diabetes mellitus, smoking, severe cough, straining at stool, and weight lifting. Seven patients (20%) were under medication related to bleeding diathesis. The values of the blood coagulation parameters were within the normal limits in all patients. Twenty-nine patients (83%) had elevated blood pressure during the ophthalmological examination. Our study provides documentation regarding the potential risk factors associated with SCH. It is interesting to observe the high incidence of hypertension among the patients with SCH. Therefore, it is highly recommended that the blood pressure be checked in all patients with SCH and that the patients be referred to a general practitioner for further management if indicated.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e6
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/44
2014-03-08T11:34:14Z
eyereports:ORIG
nmb a2200000Iu 4500
"110923 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.44
doi
dc
Changes in ocular flow induced by hypo- and hypercapnia relate to static visual acuity in humans
Hayashi, Naoyuki
Institute of Health Science and Graduate School of Human-Environment Studies, Kyushu University, Kasuga
Ikemura, Tsukasa
Institute of Health Science and Graduate School of Human-Environment Studies, Kyushu University, Kasuga
Someya, Nami
Institute of Health Science and Graduate School of Human-Environment Studies, Kyushu University, Kasuga
We investigated whether the change in ocular blood flow, induced by hypo- and hypercapnia, is related to static visual acuity. Eleven healthy subjects (26±5 years) underwent three treatments. A three-treatment three-period crossover design was used. In the hypocapnia treatment (HYPO), the subjects controlled their minute ventilation (VE) to a target of 25 L/min for 6 min. In the hypercapnia treatment (HYPER), the subjects inspired high-fraction CO2 gas (FICO2 = 4%) for 6 min. In the control treatment (CON), VE was not manipulated. We measured choroidal and retinal blood flow by laser speckle flowmetry as ocular blood flow, and static visual acuity using the Landolt C chart. End-tidal partial pressure of CO2 differed significantly among HYPO, HYPER and CON (21±1, 48±1, and 42±1 mmHg, respectively). Retinal blood flow decreased significantly from the baseline in HYPO (-22±5%), but increased significantly in HYPER (+3±9%) compared to CON. Decimal visual acuity was significantly lower in HYPO than in the CON (0.21±0.1 vs. 0.24±0.1 P<0.05). These results suggest that changes in ocular blood flow induced by changes in arterial CO2 partial pressure influences visual acuity.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e8
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/45
2014-03-08T11:34:14Z
eyereports:ORIG
nmb a2200000Iu 4500
"110928 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.45
doi
dc
Diabetes and corneal endothelial cell characteristics: a study based on Eye Bank data
Brown, Geoffrey
Arkansas Lions Eye Bank and laboratory, University of Arkansas for Medical Sciences, Little Rock, AR
Siegel, Eric
Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR
Staples, Steve
Arkansas Lions Eye Bank and laboratory, University of Arkansas for Medical Sciences, Little Rock, AR
Doyle, Jennifer
Arkansas Lions Eye Bank and laboratory, University of Arkansas for Medical Sciences, Little Rock, AR
Chang, Jason Y.
Department of Neurobiology and Developmental Sciences; Department of Ophthalmology, Jones Eye Institute, University of Arkansas for Medical
Sciences, Little Rock, AR
The aim of the article is to determine whether corneal endothelial cell density and other characteristics, such as cell area, pleomorphism and polymegathism, are affected by diabetes. Corneal endothelial cell density and other characteristics of donor eyes collected during 2007 and 2008 in a local Eye Bank were measured by the HAI Eyebank Specular Microscope System. Adult donors aged 21 or older who consented to research were divided into healthy versus compromised eye-status groups based on eye disease or past eye surgeries. Differences in corneal measures between diabetic and non-diabetic subjects were analyzed separately in each group via Mixed Models ANCOVA, with Diabetes as the fixed effect, Donor as the random effect, and Age as the continuous covariate. A total of 253 subjects met study criteria, of which 81 (32%) had diabetes. In the 180 subjects with healthy eye status, the medians (ranges) of age were 62 (29-78) years among 52 diabetics (29%), versus 57 (21-79) years among non-diabetics (P=0.013). In the 73 subjects with compromised eye status, the medians (ranges) of age were 70 (32-78) years among 29 diabetics (40%), versus 70 (29-79) years among nondiabetics (P=0.77). Between diabetics and non-diabetics, eye disease and past eye surgeries were well-balanced in the compromised eye-status group, while race and sex were wellbalanced in both eye-status groups. Results from separate analyses on the two groups indicated that diabetes did not affect corneal cell density or other corneal-cell characteristics analyzed. Even though diabetics constituted a large percentage of the Eye Bank donor population, this disease did not have a statistically significant impact on corneal endothelial cell density, cell area, pleomorphism or polymegathism.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e9
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/46
2014-03-08T11:34:14Z
eyereports:ORIG
nmb a2200000Iu 4500
"111128 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.46
doi
dc
The use of ocular coherence tomography in evaluating optic nerve health in eyes with large disc size
Weiss, Guy A.
Department of Medicine, University at Buffalo, Buffalo, NY
Wollstein, Gadi
University of Pittsburgh Medical Center Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
Naveh, Lilly
Edith Wolfson Medical Center, Department of Ophthalmology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
Landoy-Kalev, Maya
Edith Wolfson Medical Center, Department of Ophthalmology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
Ga'aton, Dany
Rabin Center, Department of Ophthalmology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
Burgansky-Eliash, Zvia
Edith Wolfson Medical Center, Department of Ophthalmology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
Large discs are often associated with large cups; in order to exclude glaucomatous cupping a good objective tool is needed. The purpose of this study is to evaluate ocular coherence tomography (OCT) optic nerve head (ONH) parameters as indicators of ocular health in subjects with large discs. Eighty-one eyes of 53 healthy patients were evaluated; 46 eyes had large discs (disc area ≥2.6 mm2) and 35 eyes had regular size discs (disc area <2.6 mm2). All subjects underwent OCT. All ONH parameters were documented, including vertical integrated rim area (VIRA), horizontal integrated rim width (HIRW), rim area, cup area, cup-to-disc (CD) area ratio, horizontal cup to disc ratio (HCDR), vertical cup to disc ratio (VCDR), cup area topography, and cup volume. In addition, OCT retinal nerve fiber layer (RNFL) global mean thickness and four quadrants mean thicknesses were analyzed. All cup parameters were significantly higher in the large disc group compared to the normal disc group. The parameters estimating the rim varied between the groups: in the large disc group VIRA was significantly lower while HIRW was significantly higher, compared to the control group. Rim area was the only parameter with similar values in both groups (1.52±0.24 mm2 and 1.6±0.3 mm2 in the large and regular disc groups, respectively). Correlation analysis revealed significant positive association between disc area and cup parameters in the large disc group. In contrast, in the regular disc group, disc area was positively associated with rim parameters. Rim area might serve as an indicator for ocular health in large discs with large cups.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e11
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/47
2014-03-08T11:34:14Z
eyereports:ORIG
nmb a2200000Iu 4500
"111201 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.47
doi
dc
Optic disc parameters in manifest and suspected glaucoma
Wanger, Peter
Department of Clinical Neuroscience, Ophthalmology & Vision, Karolinska Institutet, Stockholm
Vancea, Lucian
Eye Clinic, Sundsvalls hospital, Sundsvall
Martin, Lene
Department of Clinical Neuroscience, Ophthalmology & Vision, Karolinska Institutet, Stockholm; Academy of Health and Welfare, Mälardalen University, Eskilstuna
Structure and function measurements are important in glaucoma management. Digital fundus photography has become a standard procedure and the Heidelberg Retina Tomograph (HRT), commonly used by glaucoma specialists, provides a glaucoma probability score (GPS). The visual field index (VFI) is a novel statistic, aiming to facilitate follow-up of glaucoma patients. The aim of this study was to compare the results from the digital analysis of fundus photographs with HRT measurements including GPS and VFI in patients with ocular hypertension, suspect glaucoma or glaucoma, and if possible define an optic disc index, useful in glaucoma diagnosis. Fifty-eight consecutive patients from a glaucoma service were included. Optic disc parameters (disc and cup areas) were measured on digital fundus photographs, using a semi-automatic method, and compared with the GPS from the HRT and the VFI from standard automated perimetry. A significant relationship was observed between the GPS group classification (normal, borderline, or abnormal) and VFI classification (normal or abnormal), both when the GPS borderline group was regarded as normal (P = 0.0038 Fisher test) and as abnormal (P=0.0179, kappa = 0.33). No significant relationship was observed between VFI and optic disc parameters. The threedimensional information in the GPS appears to be more related to visual function, as measured by VFI, than the planimetric measures of the optic disc.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e12
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/48
2014-03-08T11:34:14Z
eyereports:ORIG
nmb a2200000Iu 4500
"111219 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.48
doi
dc
Detection of Helicobacter Pylori in the lacrimal sac mucosa of the patients with primary acquired nasolacrimal duct obstruction
Owji, Naser
Poostchi Eye Research Center, Shiraz University of Medical Sciences, Shiraz
Abtahi, Seyed Mohammad Bagher
Department of Ophthalmology, Khallili Hospital, Shiraz University of Medical Sciences, Shiraz
Azarpira, Negar
Organ Transplant Research Center, Shiraz University of Medical Sciences, Shiraz
Helicobacter pylori have been detected in sinonasal mucosa in both normal and pathologic condition. The nasolacrimal duct is within the medial wall of maxillary sinus and open into the nasal cavity, so ascending colonization of nasolacrimal duct and lacrimal sac is possible. The aim of this study is to investigate the presence of H. pylori by polymerase chain (PCR) reaction in the nasal and lacrimal sac mucosa of the patients with primary acquired nasolacrimal duct obstruction. Eighty patients with primary acquired nasolacrimal duct obstruction who were scheduled for dacryocystorhinostomy enrolled in the study. The patients were asked if they suffered from the classic symptoms of gastroesophageal reflux disease (heart burn, regurgitation, and acid taste). Tissue samples from the lacrimal sac mucosa and nasal mucosa were obtained during dacryocystorhinostomy surgery. The tissues were analyzed for detection of H. pylori DNA by PCR. The mean age of patients was 41.96±14.7 years (age range, 17-84 Years). PCR for H. pylori DNA was positive in the nasal mucosa in 3 patients, in the lacrimal sac mucosa in 2 patients and in both nasal mucosa and lacrimal sac mucosa in 1 patient. Classic symptoms of gastroesophageal reflux disease were found in 16 patients (20%). It is possible to detect H. pylori in the lacrimal sac mucosa of some patients with primary acquired nasolacrimal duct obstruction. More comprehensive studies are needed to determine whether H. pylori plays an etiopathologic role in the development of primary acquired nasolacrimal duct obstruction.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
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http://eyereports.org/index.php/eyereports/article/view/eye.2011.e14
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/49
2014-03-08T11:34:14Z
eyereports:CASE
nmb a2200000Iu 4500
"110627 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.49
doi
dc
Bilateral pterygium in the two siblings
Ciftci, Suleyman
Department of Ophthalmology, Diyarbakır Training and Research Hospital, Diyarbakir
Ciftci, Leyla
Department of Cardiology, Faculty of Medicine, Dicle University, Diyarbakir
Pterygia are fibrovascular connective tissue overgrowths of bulbar conjunctiva onto the cornea. There is a worldwide distribution of pterygium, but it occurs more commonly in warm, dry climates. Patients younger than the age of 15 rarely acquire a pterygium. We report a case of bilateral nasal pterygium in two siblings. A 10-year-old boy and a 12-year-old girl who are siblings presented with bilateral nasal pterygium. While pterygium is a common disorder, its bilaterality in young people is not a common condition. This report is the first known report in the peer-reviewed medical literature of patients with bilateral nasal pterygium in siblings younger than the age of 15.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
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http://eyereports.org/index.php/eyereports/article/view/eye.2011.e1
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/50
2014-03-08T11:34:14Z
eyereports:CASE
nmb a2200000Iu 4500
"110609 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.50
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dc
Enucleation assisted with filler for open-globe injury
Takahashi, Ayako
Department of Ophthalmology, Kyoto Medical Center
Akimoto, Masayuki
Department of Ophthalmology and Clinical Research Institute, Kyoto Medical Center, National
Hospital Organization, Kyoto Medical Center
Hama, Sachiyo
Department of Ophthalmology, Kyoto Medical Center
Shirai, Yoko
Department of Dentistry, Kyoto Medical Center
Minamiguchi, Sachiko
Department of Pathology, Kyoto Medical Center
In cases of severe open-globe injury, it is often difficult to reconstruct the globe and maintain visual acuity. Ocular globe enucleation may decrease the risk of sympathetic ophthalmia in the fellow eye. However, the surgical procedure is difficult to perform with an open globe, because the injured globe is inclined to collapse. We report the case of an enucleation for an open-globe injury in which we used alginate, which is often used for dental impressions, as filler for the collapsed globe. We were able to maintain the resistance of the globe sufficiently well enough to perform the procedure easily and without complication. Thus, alginate may be a novel aid to assist in enucleation by preserving globe resistance.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e2
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/51
2014-03-08T11:34:14Z
eyereports:CASE
nmb a2200000Iu 4500
"110816 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.51
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dc
A rare case of WAGR syndrome with Peter anomaly
Adyanthaya, Rohit S.
Wilmer Ophthalmological Institute, the Johns Hopkins University School of Medicine, Baltimore, Maryland
Repka, Michael X.
Wilmer Ophthalmological Institute, the Johns Hopkins University School of Medicine, Baltimore, Maryland
We report a case of the WAGR syndrome associated with the Peter anomaly. A 6-day-old baby boy was found to have bilateral corneal opacities, 360 degrees of iris hypoplasia and cataracts. Physical examination revealed bilateral undescended testicles. Family history was unremarkable and genetic testing revealed a deletion 11p11.2-13 indicating WAGR syndrome. A Wilms tumor developed and was removed at age 2 years. There was moderate developmental delay. The occurrence of WAGR syndrome with Peter anomaly has been reported in three other patients to our knowledge.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e4
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/52
2014-03-08T11:34:14Z
eyereports:CASE
nmb a2200000Iu 4500
"110912 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.52
doi
dc
Oncocytoma of the upper conjunctival fornix
Al-Mohtaseb, Zaina
Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA.
Lee, Seongmu
Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA.
Yen, Michael T.
Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA.
Oncocytomas are tumors characterized by large, eosinophilic epithelial cells with abundant mitochondria that form ductular or glandular spaces. While these tumors have been described in other organs, those of the ocular adnexa occur infrequently, with the caruncle being the most common site of involvement. Conjunctival oncocytomas are extremely rare and are believed to arise from the ductal elements of the lacrimal gland proper and the accessory lacrimal glands of the conjunctiva. We describe the clinical and histological features of a case of an oncocytoma presenting as an atypically located superior fornix mass in a 78-yearold female, with a review of the literature.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e7
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/53
2014-03-08T11:34:14Z
eyereports:CASE
nmb a2200000Iu 4500
"110923 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.53
doi
dc
Conjunctival blue nevus
Chen, Joseph Juyo
Baylor College of Medicine
Department of Ophthalmology
Lee, Seongmu
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX
Yen, Michael T.
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX
The authors report a case of a conjunctival blue nevus and review the literature pertaining to these pigmented lesions in this location, describing clinical and histological report of a patient with a blue nevus of the palpebral conjunctiva with a literature review. A 64-year-old white female was evaluated for a darkening pigmented lesion of the left lower palpebral conjunctiva. Examination revealed a 3 mm x 6mm blue-black lesion with sharply demarcated edges and an irregular border. Histopa - thology showed plump spindle-shaped, pigmented melanocytic cells revealing a branching network of dendritic processes with small, elongated, and hyperchromatic nuclei consistent with a common blue nevus. No recurrence was noted at 9-month follow-up. Blue nevi of the conjunctiva are lesions that have a low risk for malignant transformation but can appear clinically similar to primary acquired melanosis or melanoma. Blue nevi of the conjunctiva are rare and represent 0.5%-3.0% of pigmented conjunctival lesions. There was one reported case in a literature search of a malignant melanoma arising from a conjunctival cellular blue nevus. Treatment is complete wide excisional biopsy.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e10
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/54
2014-03-08T11:34:14Z
eyereports:CASE
nmb a2200000Iu 4500
"111111 2011 eng "
2039-4756
2039-4748
10.16964/er.v1i1.54
doi
dc
Idiopathic intracranial hypertension: a possible association with Imatinib
Palmowski-Wolfe, Anja M.
University of Basel, Department of Ophthalmology, Basel
Pape, Eva
University Basel, Department of Neurology, Basel
Baumann, Thomas
Neurozentrum Bern, Bern
Todorova, Margarita G.
University of Basel, Department of Ophthalmology, Basel
Idiopathic intracranial hypertension (IIH) is characterized by an increased intracranial pressure in the absence of a tumor and in the absence of a venous thrombosis. Associated risk factors include obesity and several medications such as tetracyclines. We report a 60-year-old patient who developed IIH under treatment with imatinib. To our knowledge such a possible connection has not been reported in the literature, even though intracranial hypertension is now listed as a rare possible side effect of treatment with imatinib in the Swiss List of Medications Arzneimittelkompendium. It remains to be seen, if further case reports will support this observation.
Ophthoscience Publishers, Baltimore, Maryland, USA
2011-06-09 00:00:00
application/pdf
http://eyereports.org/index.php/eyereports/article/view/eye.2011.e13
Eye Reports; Vol. 1 No. 1 (2011)
eng
Copyright (c)
oai:eyereports.org:article/56
2015-02-15T16:05:10Z
eyereports:CASE
nmb a2200000Iu 4500
"150101 2015 eng "
2039-4756
2039-4748
10.16964/er.v3i1.56
doi
dc
Tubulointerstitial nephritis and uveitis syndrome (TINU syndrome) associated with Epstein-Barr virus
Jimenez, Beatriz
Ibanez-Alperte, Juan
Perez-Garcia, Diana
Minguez, Enrique
Cristobal, Jose A
Moros, Manuel
Purpose.
To report a case of tubulointerstitial nephritis associated with uveitis (TINU) syndrome associated with Epstein-Barr virus, which presented aggressive bilateral uveitis.
Methods.
Clinical evaluation, serologic testing, and renal biopsy were performed on a 16 year-old boy who presented with bilateral visual loss and constitutional symptoms.
Results.
Slit lamp biomicroscopy revealed bilateral anterior uveitis with posterior synechiae in both eyes. He was commenced on topical and systemic corticoid treatment. Systemic evaluation revealed renal failure. Renal biopsy confirmed the diagnosis of TINU syndrome. IgM serology was positive for Epstein-Barr virus. While the renal response was good, the uveitis required immunosuppression which resulted in resolution.
Conclusions.
There have been only 3 previously reported cases of TINU syndrome associated with acute Epstein-Barr infection. In TINU syndrome, it has been reported that microorganisms may act as triggers of the disease in patients who are genetically predisposed. TINU syndrome should be considered in the differential diagnosis of uveitis with constitutional symptoms.
Ophthoscience Publishers, Baltimore, Maryland, USA
2015-02-15 07:14:01
application/pdf
http://eyereports.org/index.php/eyereports/article/view/56
Eye Reports; Vol. 3 No. 1 (2015)
eng
Copyright (c)
oai:eyereports.org:article/57
2018-06-28T11:37:54Z
eyereports:ORIG
nmb a2200000Iu 4500
"180301 2018 eng "
2039-4756
2039-4748
10.16964/er.v4i1.57
doi
dc
The effect of intraocular pressure lowering medications on the pressure spike associated with intravitreal injection
Pokrosvkaya, Olya
Mater Miscericordiae University Hospital, Dublin, Ireland
Dooley, Ian
Babiker, Salma
Croghan, Catherine
Hartnett, Claire
Cullinane, Anthony
Purpose. This study investigates whether the post intravitreal injection intraocular pressure (IOP) spike is modifiable with the use of prophylactic apraclonidine and dorzolomide.
Methods. The study design is a prospective, randomized controlled clinical trial. 80 eyes undergoing intravitreal injection of anti-VEGF agent were studied. A control group (n = 42) received no IOP lowering drops, and a study group (n = 38) received topical apraclonidine and dorzolamide 30 to 40 minutes before the intravitreal injection. IOP measurements were taken in both groups using the Perkins tonometer at baseline, immediately before and after the injection, 5 minutes post-injection, and 15 minutes post-injection.
Results. Mean IOP immediately post injection in the study group compared to the control group was lower: 26.71 mmHg versus 32.73 mmHg (p=0.026). The main outcome measure was the area under the curve (AUC), reflecting the trend of IOP post injection. The AUC was lower in the study group compared to the control group (Mann-Whitney U test, p=0.046).
Conclusions. The use of prophylactic apraclonidine and dorzolamide is effective in modifying the post-injection IOP spike. IOP lowering prophylaxis may be considered in patients with a high baseline IOP.
Ophthoscience Publishers, Baltimore, Maryland, USA
2018-04-03 10:11:53
application/pdf
http://eyereports.org/index.php/eyereports/article/view/57
Eye Reports; Vol. 4 No. 1 (2018)
eng
Copyright (c)
oai:eyereports.org:article/58
2018-06-28T11:45:44Z
eyereports:ORIG
nmb a2200000Iu 4500
"180403 2018 eng "
2039-4756
2039-4748
10.16964/er.v4i1.58
doi
dc
Spectral domain optical coherent tomography demonstrates structural retinal changes in isolated cilioretinal artery occlusion
Bagheri, Mansooreh
Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Ashraf, Hossein
Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Nowroozzadeh, Mohammad Hossein
Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
This report demonstrates the structural retinal changes observed in-vivo by spectral domain optical coherent tomography (SD-OCT) in a case of isolated cilioretinal artery occlusion. A 32-year-old woman presented one week following acute sudden painless loss of vision. Ophthalmoscopy revealed macular edema and a cherry red spot. Fluorescein angiography one week post-infarction demonstrated a large patch of macular hypoflorescence in the distribution of the cilioretinal artery, with perfusion of the cilioretinal artery. Within this same macular distribution, SD-OCT demonstrated increased reflectivity, with increased reflectivity of the inner nuclear, inner plexiform, and ganglion cell layers. A sharp boundary was present between normal and infarcted macula on SD-OCT imaging. SD-OCT is a useful tool for diagnosing and identifying the extent of retinal vascular occlusion.
Ophthoscience Publishers, Baltimore, Maryland, USA
2018-04-03 10:11:53
application/pdf
http://eyereports.org/index.php/eyereports/article/view/58
Eye Reports; Vol. 4 No. 1 (2018)
eng
Copyright (c)
oai:eyereports.org:article/60
2018-06-28T11:36:32Z
eyereports:ORIG
nmb a2200000Iu 4500
"180628 2018 eng "
2039-4756
2039-4748
10.16964/er.v4i1.60
doi
dc
An atypical presentation of pseudoxanthoma elasticum (PXE) without angioid streaks or peau d’orange
Chan, Choi Mun
Singapore National Eye Centre
Omar, Amer
Moorfields Eye Hospital
Pefkianaki, Maria
Rajendram, Ranjan
Paige, David
Cerio, Rino
Michaelides, Michel
Pseudoxanthoma Elasticum (PXE) is an inherited multi-system disorder with potentially fatal complications. Biallelic mutations in the ABCC6 gene, which encodes an ATP-binding cassette transporter, have been identified to underlie this disease. Patients with pseudoxanthoma elasticum (PXE) classically have angioid streaks and peau d’orange. In this report, we present the case of a 9-year-old girl with histologically confirmed PXE, who did not have either angioid streaks or peau d’orange in either eye. Her only ophthalmic finding was the presence of bilateral optic disc drusen. This atypical presentation of PXE highlights that the presence of optic disc drusen in the absence of other signs should alert the physician to consider PXE.
Ophthoscience Publishers, Baltimore, Maryland, USA
2018-04-03 10:11:53
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http://eyereports.org/index.php/eyereports/article/view/60
Eye Reports; Vol. 4 No. 1 (2018)
eng
Copyright (c)
oai:eyereports.org:article/62
2018-06-28T11:36:32Z
eyereports:ORIG
nmb a2200000Iu 4500
"180403 2018 eng "
2039-4756
2039-4748
10.16964/er.v4i1.62
doi
dc
Oncocytoma of the Lacrimal Duct: A Rare Tumor of the Eyelid
Toru, Havva Serap
Akdeniz University School of Medicine Department of Pathology
Uzunoglu, Ebru Erol
Dr. Munif Islamoglu Governmet Hospital, Department of Pathology, Kastamonu, Turkey
Arican, Cigdem Dicle
Dr. Munif Islamoglu Governmet Hospital, Department of Pathology, Kastamonu, Turkey
Demirhan, Beyhan
ClinLab Ankara Laboratory, Ankara/Turkey
This report demonstrates a rare case of lacrimal duct obstruction from a rare tumor. A 69 year-old otherwise healthy woman presented with a small nodular lesion in the plica semilunaris of left upper eyelid. Microscopic evaluation of the excised tumor revealed a oncocytoma.
Ophthoscience Publishers, Baltimore, Maryland, USA
2018-04-03 10:11:53
application/pdf
application/pdf
http://eyereports.org/index.php/eyereports/article/view/62
Eye Reports; Vol. 4 No. 1 (2018)
eng
Copyright (c)
oai:eyereports.org:article/63
2015-02-15T17:18:58Z
eyereports:CASE
nmb a2200000Iu 4500
"150101 2015 eng "
2039-4756
2039-4748
10.16964/er.v3i1.63
doi
dc
Ocular melanocytosis and secondary glaucoma in a child
Kumar, Logandran Vijaya
Ming, Vivian Gong Hee
Glaucoma at young age is an unusual presentation of congenital ocular melanocytosis. We report a young patient with a unilateral splinter disc hemorrhage, mild asymmetric optic nerve cupping, and increased intraocular pressures, suggestive of glaucoma, associated with bilateral ocular melanocytosis. While glaucoma and/or increased intraocular pressures have been reported in oculodermal melanocytosis in the adult population, there are only rare reports of congenital ocular melanocytosis associated with secondary glaucoma in a child. Glaucoma is believed to result from melanocytic involvement of the anterior chamber angle and trabecular meshwork with resultant obstruction of outflow.
Ophthoscience Publishers, Baltimore, Maryland, USA
2015-02-15 07:14:01
application/pdf
http://eyereports.org/index.php/eyereports/article/view/63
Eye Reports; Vol. 3 No. 1 (2015)
eng
Copyright (c)
oai:eyereports.org:article/64
2015-02-15T17:40:34Z
eyereports:CASE
nmb a2200000Iu 4500
"150101 2015 eng "
2039-4756
2039-4748
10.16964/er.v3i1.64
doi
dc
Nd:YAG laser hyaloidotomy in a case of Valsalva retinopathy with premacular hemorrhage
Guler, Mete
Guler, Ozlem
Bilgin, Burak
Intraretinal, preretinal, and vitreous hemorrhages in Valsalva retinopathy result from retinal capillary rupture following sudden increased retinal venous pressure from a rise in intrathoracic or intraabdominal pressure. While preretinal hemorrhages may resolve on their own or may be treated with vitrectomy, we report a case of Valsalva retinopathy with a dense premacular hemorrhage which was successfully treated with Nd:YAG laser hyaloidotomy. A healthy 27-years-old man presented with sudden painless visual loss after heavy cement bag lifting. His visual acuity was count fingers in the affected eye. A dilated fundus examination revealed a large dome shaped preretinal hemorrhage. Nd:YAG laser hyaloidotomy was performed at the inferotemporal margin of the preretinal hemorrhage. Within two weeks, the visual acuity improved to 20/20 and there was near complete resolution of the preretinal hemorrhage. Non-visually-significant pigment epithelial injury was noted at the site of the laser application. Nd:YAG laser hyaloidotomy may be a safe and effective therapeutic option in select patients with Valsalva retinopathy with preretinal hemorrhage.
Ophthoscience Publishers, Baltimore, Maryland, USA
2015-02-15 07:14:01
application/pdf
http://eyereports.org/index.php/eyereports/article/view/64
Eye Reports; Vol. 3 No. 1 (2015)
eng
Copyright (c)
oai:eyereports.org:article/65
2015-02-15T17:48:59Z
eyereports:ORIG
nmb a2200000Iu 4500
"150101 2015 eng "
2039-4756
2039-4748
10.16964/er.v3i1.65
doi
dc
The changing rates and indications of optical coherence tomography and fundus fluorescein angiography over 5 years
Dooley, Ian
Ibrahim, Farah
O'Connor, Gerry
Purpose. To evaluate the relative frequency of use of fundus fluorescein angiography (FFA) following the introduction of optical coherence tomography (OCT) at a tertiary university ophthalmology practice.
Methods. We retrospectively analyzed the demand for and indications of all requests for FFA or OCT during the five years from 2007 to 2011, inclusively, at our tertiary care university hospital department of ophthalmology.
Results. In January 2007, out of 194 total imaging studies requested and performed, there were 85 OCTs (43.8% of total imaging studies) and 109 FFAs (56.2%). By January 2011, out of 172 total imaging studies requested and performed, there were 127 OCT cases (73.8%) and 45 FFA cases (26.2%). FFAs for macular degeneration and diabetic maculopathy accounted for 54.3% of all imaging in 2007, but five years later had fallen to just 22%.
Conclusions. A decrease in the number of FFAs requested and performed was associated an increase in number of OCTs, over the five year period. While this pattern was observed in a single relatively small tertiary care setting, this study may be the first report in the peer-reviewed medical literature of this trend. The relative safety profile and convenience of OCT as compared to FFA may be a primary factor in this shift.
Ophthoscience Publishers, Baltimore, Maryland, USA
2015-02-15 07:14:01
application/pdf
http://eyereports.org/index.php/eyereports/article/view/65
Eye Reports; Vol. 3 No. 1 (2015)
eng
Copyright (c)
oai:eyereports.org:article/66
2019-05-18T16:42:17Z
eyereports:ART
nmb a2200000Iu 4500
"190401 2019 eng "
2039-4756
2039-4748
10.16964/er.v5i1.66
doi
dc
Self-reported eye diseases among American Indian individuals with type 2 diabetes from the northern Midwest
Aronson, Benjamin D
University of Minnesota
Gregoire, Anna RF
Kading, Margarette L
RedBrook, Shannon
Wilson, Ryan
Walls, Melissa
Purpose. To determine the prevalence of self-reported eye diseases and self-reported utilization of dilated eye exams among a sample of American Indian (AI) individuals with type 2 diabetes.
Methods. AI adults with type 2 diabetes utilizing health care at two reservation clinics were randomly sampled and recruited for interviewer-assisted paper surveys. The prevalence of eye diseases was compared across gender, age, income, and educational attainment.
Results. The prevalence of self-reported diabetic retinopathy, cataract, macular degeneration, and glaucoma were 9.4%, 26.7%, 5.2%, and 10.6% respectively, and 59.2% reported past year dilated eye exams. Older participants were more likely to report cataract (p < 0.001) and glaucoma (p = .003). Those with lower income were more likely to report cataract (p = 0.001).
Conclusions. Rates of self-reported eye diseases in this sample were higher, and dilated eye exams lower than other samples of the general United States population with diabetes, suggesting improvement can be made to improve the provision of care for AI individuals with type 2 diabetes.
Ophthoscience Publishers, Baltimore, Maryland, USA
2019-05-18 09:05:49
application/pdf
http://eyereports.org/index.php/eyereports/article/view/66
Eye Reports; Vol. 5 No. 1 (2019)
eng
Copyright (c)
oai:eyereports.org:article/70
2018-06-28T11:45:00Z
eyereports:ORIG
nmb a2200000Iu 4500
"180403 2018 eng "
2039-4756
2039-4748
10.16964/er.v4i1.70
doi
dc
Trabeculectomy with an implantable biodegradable collagen matrix (Ologen) for the management of glaucoma associated with cavernous sinus arteriovenous fistula
Grover, Isha Gulati
LV Prasad Eye Institute. Hyderabad. India
Senthil, Sirisha
LV Prasad Eye Institute. Hyderabad. India
Chandrasekhar, Garudadri
LV Prasad Eye Institute. Hyderabad. India
A 58-year-old gentleman presented with open angle glaucoma secondary in the right eye secondary to a cavernous sinus arteriovenous fistula. Since the intraocular pressure control was refractory to medical management, an augmented filtration surgery was planned. Trabeculectomy in eyes with raised episcleral venous pressure is associated with a substantially greater risk of intraoperative or post-operative choroidal effusion and suprachoroidal haemorrhage. This patient was successfully managed by performing trabeculectomy with an implantable biodegradable collagen, type 1 atelocollagen, matrix (Ologen), without any sight threatening complications.
Ophthoscience Publishers, Baltimore, Maryland, USA
2018-04-03 10:11:53
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application/pdf
http://eyereports.org/index.php/eyereports/article/view/70
Eye Reports; Vol. 4 No. 1 (2018)
eng
Copyright (c)
oai:eyereports.org:article/72
2022-07-27T01:26:36Z
eyereports:ORIG
nmb a2200000Iu 4500
"200304 2020 eng "
2039-4756
2039-4748
10.16964/er.v6i1.72
doi
dc
Papilledema secondary to parietal dermoid - epidermoid cyst with superior sagittal sinus compression
Ní Mhéalóid, Áine
Mater Misericordiae University Hospital
Siah, We Fong
Mater Misericoridiae University Hospital
Dermoid and epidermoid cysts are benign slow growing tumors that arise from ectodermal tissue. In this case report, a 32-year-old gentleman presented with a right posterior parietal dermoid - epidermoid cysts resulting in superior sagittal sinus compression. Clinical examination disclosed enlarged blindspot formation in both eyes and bilateral papilledema. He was treated with a low-pressure shunt, resulting in resolution of the papilledema and his symptoms. In a search of the peer-reviewed medical literature (using MEDLINE and cross-referenced literature), this report may be the second to report papilledema secondary to an intracranial dermoid or epidermoid cyst with superior sagittal sinus compression.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-03-16 07:34:31
application/pdf
http://eyereports.org/index.php/eyereports/article/view/72
Eye Reports; Vol. 6 No. 1 (2020)
eng
Copyright (c)
oai:eyereports.org:article/73
2019-05-18T16:53:19Z
eyereports:ART
nmb a2200000Iu 4500
"190401 2019 eng "
2039-4756
2039-4748
10.16964/er.v5i1.73
doi
dc
Racial disparity in the prevalence of glaucoma in the United States
Allison, Karen
Mt. Sinai Hospital
Brooklyn Veterans Hospital
Glaucoma, a disorder of the optic nerve, occurs when the intraocular pressure, a risk factor for glaucoma, is elevated, leading to an eventual loss of sight. This study’s purpose is to evaluate the racial disparity in the prevalence of glaucoma and present different ways to improve early diagnosis and treatment outcomes among glaucoma patients. A literature review is performed using the PubMed database to examine the associated risk factors and prevalence of glaucoma among racial grouping. The literature indicates that early diagnosis and treatment is the most effective approach for combating the considerable social and economic cost of blindness caused by this disease. Studies also suggest that outreach, educational, and screening programs to combat eye diseases should be geared towards high-risk populations such as African Americans and Latinos, as these groups tend to be less aware of their eye problems and have limited access to treatments. The establishment of projects to prevent blindness from glaucoma will alert medical care providers of the need for early evaluation for risk factors, which in turn will allow for the allocation of resources to reimburse for the treatment provided.
Ophthoscience Publishers, Baltimore, Maryland, USA
2019-05-18 09:05:49
application/pdf
http://eyereports.org/index.php/eyereports/article/view/73
Eye Reports; Vol. 5 No. 1 (2019)
eng
Copyright (c)
oai:eyereports.org:article/74
2019-05-18T16:57:51Z
eyereports:ART
nmb a2200000Iu 4500
"190401 2019 eng "
2039-4756
2039-4748
10.16964/er.v5i1.74
doi
dc
Form fruste pachydermoperiostosis associated with ptosis and floppy eyelid syndrome
Rubinov, Avi
University of Calgary, division of surgery, department of ophthalmology
Bart, Bevin
Department of Anesthesia, Rocky view general hospital, Calgary, Alberta, Canada.
Oryschak, Allan
Department of Pathology, Rocky view general hospital, Calgary, Alberta, Canada
Weis, Ezekiel
Division of Ophthalmology, Department of Surgery, Faculty of Medicine, University of Calgary, Alberta, Canada.
Ting, Andrew
Division of Ophthalmology, Rocky view general hospital, Calgary, Alberta, Canada
Pachydermoperiostosis (PDP), also known as idiopathic or primary hypertrophic osteoarthropathy or Touraine-Solente-Gole Syndrome, is a rare genetic disorder affecting skin and bone, consisting of pachydermia and periostosis. Pachydermia is a thickening and furrowing of the skin and face in a manner that resembles the skin of a pachyderm. Periostosis is periosteal new bone formation in the long bones. In this report, a 16-year-old boy presented with bilateral ptosis and floppy eyelids. He was successfully treated with bilateral upper eyelid pentagonal wedge resections. Histopathology of the excised tissue demonstrated mild epidermal acanthosis and marked increased dermal collagen with thickening of individual fibers, consistent with pachydermia, as well as papillary conjunctival inflammation and Meibomian glands hyperplasia with ductal dilatation, consistent with floppy eyelid syndrome. Radiographic imaging did not demonstrate any signs of periostosis, confirming the diagnosis of form fruste PDP. In a diligent search of the peer-reviewed medical literature (using PubMed and cross-referenced literature), this case may be the first report of floppy eyelid syndrome and ptosis associated with form fruste PDP.
Ophthoscience Publishers, Baltimore, Maryland, USA
2019-05-18 09:05:49
application/pdf
http://eyereports.org/index.php/eyereports/article/view/74
Eye Reports; Vol. 5 No. 1 (2019)
eng
Copyright (c)
oai:eyereports.org:article/75
2018-06-28T11:36:32Z
eyereports:ORIG
nmb a2200000Iu 4500
"180628 2018 eng "
2039-4756
2039-4748
10.16964/er.v4i1.75
doi
dc
Technique to reduce failure with corneal stromal tattoo in patients with symptomatic laser peripheral iridotomy
Davies, Emma C
Masssachusetts Eye and Ear Infirmary
Saeed, Hajirah N
Massachusetts Eye and Ear Infirmary
Pineda, Roberto
Massachusetts Eye and Ear Infirmary
Purpose. This study presents two cases of persistent glare symptoms after laser peripheral iridotomy despite the patients undergoing corneal stromal tattooing with black ink placed in a manually constructed stromal pocket. Possible reasons as to why each case resulted in treatment failure are described along with a technique to reduce such failures.
Methods. The study design is a retrospective report of two cases of corneal stromal tattooing after symptomatic laser peripheral iridotomy.
Results. In both cases, failure to resolve glare symptoms was attributed to patchy pigmentation in the corneal stromal pocket that was highlighted only with retro-illumination at the slit lamp.
Conclusions. The method proposed to reduce failures is verifying with retro-illumination for defects in a corneal tattoo as a method to reduce failures.
Ophthoscience Publishers, Baltimore, Maryland, USA
2018-04-03 10:11:53
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http://eyereports.org/index.php/eyereports/article/view/75
Eye Reports; Vol. 4 No. 1 (2018)
eng
Copyright (c)
oai:eyereports.org:article/76
2019-05-18T16:33:35Z
eyereports:ART
nmb a2200000Iu 4500
"190401 2019 eng "
2039-4756
2039-4748
10.16964/er.v5i1.76
doi
dc
Conjunctival lymphangiectasis: successful surgical resection of an idiopathic case
Seven, Erbil
Yuzuncu Yil University, Ophthalmology Department
Batur, Muhammed
Yuzuncu Yil University, Ophthalmology Department
Tekin, Serek
Yuzuncu Yil University, Ophthalmology Department
Bulut, Gulay
Yuzuncu Yil University, Pathology Department
Yasar, Tekin
Yuzuncu Yil University, Ophthalmology Department
Conjunctival lymphagiectasis is a topical ocular condition characterized by swelling of conjunctiva as a result of dilated lymphatics of the bulbar conjunctiva. In this case report, a 51-year-old man presented with conjunctival swelling in the left eye. Conjunctival lymphangiectasis was diagnosed and a conjunctival resection was performed. No recurrence was found in follow-up examination at 9 months.
Ophthoscience Publishers, Baltimore, Maryland, USA
2019-05-18 09:05:49
application/pdf
http://eyereports.org/index.php/eyereports/article/view/76
Eye Reports; Vol. 5 No. 1 (2019)
eng
Copyright (c)
oai:eyereports.org:article/78
2019-05-18T16:17:31Z
eyereports:ART
nmb a2200000Iu 4500
"190401 2019 eng "
2039-4756
2039-4748
10.16964/er.v5i1.78
doi
dc
Sporadic Burkitt’s lymphoma presents as an isolated orbital disease
Ibáñez Muñoz, Ana
San Pedro Hospital
Ibáñez Muñoz, Ana
San Pedro Hospital
Ibáñez Muñoz, Ana
San Pedro Hospital
Lizuain Abadia, M. Ester
San Pedro Hospital
Lizuain Abadia, M. Ester
San Pedro Hospital
Delso Gil, Elena
San Pedro Hospital
Delso Gil, Elena
San Pedro Hospital
Velilla Osés, Sara
San Pedro Hospital
Velilla Osés, Sara
San Pedro Hospital
Burkitt’s lymphoma is a highly aggressive non–Hodgkin’s lymphoma and the fastest growing, that accounts for 3% to 5% of all lymphomas. Three clinically subtypes have been described: endemic, sporadic, and immunodeficiency-associated. The sporadic form typically presents as an abdominal mass. Orbital involvement has rarely been reported. In this case report, a 66-year-old man presented with a three-week history of vision loss and painful proptosis of the left eye. Neuro-imaging revealed a well-circumscribed solid mass of the left orbit, for which a biopsy under general anesthesia was performed. The diagnosis of Burkitt’s lymphoma was confirmed by immunohistochemistry. Chemotherapy was initiated with good clinical outcome, though there was no improvement in his visual acuity. In conclusion, Burkitt’s lymphoma must be considered in patients who present with painful proptosis and vision loss, as it is one of the fastest growing and chemosensitive malignancies, which can lead to irreversible vision loss.
Ophthoscience Publishers, Baltimore, Maryland, USA
2019-05-18 09:05:49
application/pdf
http://eyereports.org/index.php/eyereports/article/view/78
Eye Reports; Vol. 5 No. 1 (2019)
eng
Copyright (c)
oai:eyereports.org:article/81
2018-06-28T11:36:32Z
eyereports:ORIG
nmb a2200000Iu 4500
"180628 2018 eng "
2039-4756
2039-4748
10.16964/er.v4i1.81
doi
dc
Brown syndrome associated with Marcus-Gunn jaw winking ptosis
Biagini, Ilaria
AOU Careggi, University of Florence
Miele, Alba
Virgili, Gianni
Rizzo, Stanislao
Brown syndrome is a rare mechanical disorder characterized by restriction of the superior oblique trochlea-tendon complex. Marcus-Gunn jaw winking ptosis is a more common congenital oculofacial synkinesis in which blepharoptosis is associated with upper eyelid contraction that accompanies jaw movement. In this report, we present the case of a 50-year-old woman with unilateral Brown syndrome and Marcus-Gunn jaw winking ptosis in the fellow eye.
Ophthoscience Publishers, Baltimore, Maryland, USA
2018-04-03 10:11:53
application/pdf
http://eyereports.org/index.php/eyereports/article/view/81
Eye Reports; Vol. 4 No. 1 (2018)
eng
Copyright (c)
oai:eyereports.org:article/82
2020-03-27T16:16:39Z
eyereports:ART
nmb a2200000Iu 4500
"190518 2019 eng "
2039-4756
2039-4748
10.16964/er.v5i1.82
doi
dc
Epibulbar complex choristoma including lacrimal gland, cartilage, and adipose tissue
Gedar Totuk, Ozgun Melike
Bahcesehir University
Ozbaykus, Abdullah Canberk
Turkmen, Irem
Kabadayi, Kerem
Cetin, Emel Dikicioglu
Choristomas are congenital lesions which appear in abnormal regions, preserving their size and shape over years. Choristomas are named according to their tissue content: those that include more than one tissue are called complex choristomas and constitute only a small proportion of all limbal dermoids. In this case, a 9-month-old child presented with a limbal dermoid on the superotemporal aspect of his right eye. The dermoid was surgically excised because he was at risk of anisometric ambylopia due to the induced high astigmatism. Pathological examination demonstrated a complex choristoma consisting of cartilage, lacrimal gland, and mature adipocyte tissue. Complex choristomas are important in differential diagnosis of limbal dermoid.
Ophthoscience Publishers, Baltimore, Maryland, USA
2019-05-18 09:05:49
application/pdf
http://eyereports.org/index.php/eyereports/article/view/82
Eye Reports; Vol. 5 No. 1 (2019)
eng
Copyright (c)
oai:eyereports.org:article/89
2022-07-27T01:26:37Z
eyereports:ORIG
nmb a2200000Iu 4500
"200326 2020 eng "
2039-4756
2039-4748
10.16964/er.v6i1.89
doi
dc
The evaluation and correlation of subfoveal choroidal thickness and macular hole apical and basal diameters with enhanced depth imaging optical coherence tomography in patients with idiopathic macular hole
Keles, Ali
Citirik, Mehmet
Ilhan, Cagri
Teke, Mehmet Yasin
Purpose: To investigate the evaluation and correlation between apical and basal hole diameters and subfoveal choroidal thickness (SCT) in patients with idiopathic macular hole (IMH), using enhanced depth imaging optical coherence tomography (OCT).
Methods: This cross-sectional study included 30 eyes of 30 patients with IMH and 30 healthy controls eyes. The SCT of subjects were measured using enhanced depth imaging OCT and the results were compared. In the IMH group, the mean horizontal apical and basal diameters of IMH were calculated and the correlation between mean apical and basal diameters and SCT were investigated. All patients with IMH underwent vitreoretinal surgery and the SCT at third postoperative month was compared with the preoperative values.
Results: The mean age and gender distributions of the groups were similar (p =0.082 and p =0.605). The mean SCT was 241.73 ± 57.20 μm in the IMH group and 280.30 ± 72.22 μm in the control group. The SCT of the IMH group was thinner than that of the control group (p =0.025). The mean apical and basal diameters of the IMH were 395.30 ± 190.71 μm and 920.70 ± 428.19 μm, respectively. There was a significant negative correlation between mean apical diameter and SCT of IMH (r =- 0.373, p = 0.042) and there was no significant correlation between mean basal diameter and SCT of IMH (r =-0.282, p = 0.131). The mean SCT was 237.19 ± 43.61 at the third postoperative month and there was no significant difference between the postoperative and preoperative values of the IMH group (p =0.555).
Conclusion: The SCT is thinner in IMH patients than that of healthy subjects, and there is a statistically-significant negative correlation between the apical hole diameter and SCT. In the early stage (three-month postoperative) after anatomical closure of IMH with vitreoretinal surgery, the SCT does not change significantly.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-03-16 07:34:31
application/pdf
http://eyereports.org/index.php/eyereports/article/view/89
Eye Reports; Vol. 6 No. 1 (2020)
eng
Copyright (c)
oai:eyereports.org:article/90
2022-07-27T01:26:36Z
eyereports:ORIG
nmb a2200000Iu 4500
"200302 2020 eng "
2039-4756
2039-4748
10.16964/er.v6i1.90
doi
dc
Bilateral reversible visual loss secondary to undiagnosed acute porphyria in a child
See, Wendy Yen Nee
Chua, Lausanne
The porphyrias are a group of disorders, often genetic, characterized by systemic or localized accumulation of porphyrins, precursors of the iron metalloprotein heme. Acute porphyria is a descriptive category of the porphyrias in which patients present with sudden onset neurologic symptoms or attacks of pain. Ocular and visual manifestations of porphyria are rare. In this case report, a 9-year-old girl, with no past medical history, experienced bilateral visual loss. She was diagnosed with acute porphyria with autonomic dysfunction, including neuropathic abdominal pain, peripheral neuropathy, seizure, and labile hypertension. After seizure control and blood pressure regulation, the patient was treated with intravenous dextrose and a high carbohydrate diet, and her vision loss recovered to a visual acuity of 20/40 bilaterally.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-03-16 07:34:31
application/pdf
http://eyereports.org/index.php/eyereports/article/view/90
Eye Reports; Vol. 6 No. 1 (2020)
eng
Copyright (c)
oai:eyereports.org:article/91
2022-07-27T01:26:36Z
eyereports:ORIG
nmb a2200000Iu 4500
"200305 2020 eng "
2039-4756
2039-4748
10.16964/er.v6i1.91
doi
dc
Neuromyelitis optica presenting with bitemporal hemianopia
Effendi Tenang, Irina
Khaliddin, Nurliza Binti
Ramli, Norlisah
Zahari, Mimiwati
Neuromyelitis optica (NMO) is an idiopathic immune-mediated inflammatory disease of the central nervous system (CNS) characterized by severe demyelination and axonal damage with a predilection for the optic nerves and spinal cord. In this case report, a 60-year-old woman presented with decreased vision. Visual field testing initially demonstrated a bitemporal inferior quadrantinopia which progressed to a bitemporal hemianopia. The patient did not have any focal neurologic deficits. Indirect immunofluorescence testing was performed and positive for serum anti-aquaporin 4 (AQP4) antibodies indicating a diagnosis of NMO. The bitemporal hemianopia largely resolved following intravenous steroids. However, she developed a relapse of her NMO requiring restarting of the intravenous steroids. The patient was diagnosed with chiasmal neuritis. A variety of visual field defects may be seen in optic neuropathies, but typically in NMO, a central scotoma or altitudinal hemianopia is the most frequent visual field defect in patients with optic neuritis; bitemporal hemianopia is exceedingly rare.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-03-16 07:34:31
application/pdf
http://eyereports.org/index.php/eyereports/article/view/91
Eye Reports; Vol. 6 No. 1 (2020)
eng
Copyright (c)
oai:eyereports.org:article/92
2022-07-27T01:26:36Z
eyereports:ORIG
nmb a2200000Iu 4500
"200305 2020 eng "
2039-4756
2039-4748
10.16964/er.v6i1.92
doi
dc
Bilateral multifocal pseudomonas aeruginosa keratitis in a contact lens-wearing diabetic patient treated with a custom compounded 5% imipenem-cilastatin topical solution
Taskiran Comez, Arzu
canakkale onsekiz mart university
Yildiz, Aydin
Pseudomonas aeruginosa is a devastating agent of fulminant keratitis in contact lens-wearers, immunosuppressive patients, and refractive surgery patients which may lead to substantial loss of vision, and in severe cases, blindness. In this case report, a 30-year-old diabetic contact lens wearer who had history of sleeping with lenses and prolonged use of the same contact lens presented with multiple foci of keratitis in each eye. No pathogen was detected from corneal scrapings, but the contact lenses and the contact lens case were culture positive for Pseudomonas aeruginosa. The keratitis was only partially responsive to topical fortified ceftazidime, topical fortified vancomycin, and topical fluconazole. A decision was made to switch to topical imipenem-cilastatin due to the multiple risk factors, including diabetes, contact lens overuse, and bilateral multifocal corneal involvement, after which the keratitis resolved. Topical imipenem-cilastatin may be a successful alternative treatment in patients with Pseudomonas keratitis who do not respond to conventional antibiotic therapy.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-03-16 07:34:31
application/pdf
http://eyereports.org/index.php/eyereports/article/view/92
Eye Reports; Vol. 6 No. 1 (2020)
eng
Copyright (c)
oai:eyereports.org:article/96
2020-11-17T03:01:05Z
eyereports:ORIG
nmb a2200000Iu 4500
"201116 2020 eng "
2039-4756
2039-4748
10.16964/er.v7i1.96
doi
dc
Hemi-forehead lifting for upper eyelid and brow ptosis in neurofibromatosis type 1
Havuz, Erol
University of Health Sciences
A 63-year-old female patient presented with ptosis in the right eyelid, wrinkles in the right half of the forehead, and narrowing of visual field. She had been diagnosed with giant plexiform neurofibroma. In addition, she had painless, non-tender soft masses on her left shoulder and neck. The patient's ptosis and forehead wrinkles improved in the supine position but were more prevalent in the vertical position. She had undergone blepharoplasty in the previous year. She did not have any disease history other than mild ptosis in the right and a mass in the neck that was present since puberty but had grown within the last decade. Pretrichial hemi-forehead and brow lift for eyebrow ptosis and forehead wrinkles was planned and performed without any complications in the early postoperative period and no recurrence in the 18-month follow-up period.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-11-16 18:22:44
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http://eyereports.org/index.php/eyereports/article/view/96
Eye Reports; Vol. 7 No. 1 (2020)
eng
Copyright (c)
oai:www.eyereports.org:article/97
2022-07-27T01:26:30Z
eyereports:ORIG
oai:eyereports.org:article/98
2022-07-27T01:26:37Z
eyereports:ORIG
nmb a2200000Iu 4500
"200327 2020 eng "
2039-4756
2039-4748
10.16964/er.v6i1.98
doi
dc
Vision loss in older veterans is greater in rural than urban areas
McDaniel, Justin Tyler
Southern Illinois University
Albright, David L
University of Alabama
Wallace, Juliane P
Southern Illinois University
Jenkins, Wiley D
Southern Illinois University School of Medicine
Purpose: Although rurality has been shown to be a risk factor for vision loss in the general population, there are no published studies to evaluate the relative risk of vision loss in older veterans (age greater than 64 years). Given that veterans have access to a separate healthcare system, the Veterans Health Administration system, this study sought to determine whether older rural veterans had a higher prevalence of vision loss than older urban veterans.
Methods: Data for this cross-sectional study were obtained from the 2016-2018 Behavioral Risk Factor Surveillance System (BRFSS) surveys. Older veteran (n = 49,697) self-reported vision loss was regressed on rural-urban area of residence in a mixed logit model, where state of residence served as a random intercept. This study model controlled for age, race, sex, income, binge drinking behavior, cigarette use, BMI, exercise, diabetes, and mental distress.
Results: Analysis demonstrated that vision loss among older veterans was more prevalent in rural areas (6.73%, 95% CI = 6.27, 7.22) than in urban areas (5.89%, 95% CI = 5.57, 6.23). After controlling for all confounders previously described, rurality was independently associated with vision loss among older veterans (aOR = 1.12, 95% CI = 1.02, 1.23).
Conclusions: In a search of the peer-reviewed medical literature (using MEDLINE and cross-referenced literature, this study is the first to demonstrate a rural-to-urban disparity in vision loss among older veterans in the United States. The results of this study demonstrate the need for broader access to health care, including evidence-based remote or telehealth eye care screening and rehabilitation programs for rural veterans, especially within the Veterans Health Administration system.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-03-16 07:34:31
application/pdf
http://eyereports.org/index.php/eyereports/article/view/98
Eye Reports; Vol. 6 No. 1 (2020)
eng
Copyright (c)
oai:www.eyereports.org:article/99
2022-07-27T01:26:34Z
eyereports:ORIG
oai:www.eyereports.org:article/100
2022-07-27T01:26:34Z
eyereports:ORIG
oai:eyereports.org:article/101
2020-11-17T02:47:17Z
eyereports:ORIG
nmb a2200000Iu 4500
"201116 2020 eng "
2039-4756
2039-4748
10.16964/er.v7i1.101
doi
dc
Discovery of a novel genetic variation in papillorenal syndrome
Ortega Renedo, Irune
San Pedro Hospital
Ibáñez Muñoz, Ana
San Pedro Hospital
Ibáñez Muñoz, Cristina
San Pedro Hospital
Rozanova Klecheva, María
San Pedro Hospital
Rodríguez Vicente, Leticia
San Pedro Hospital
Sosa Durán, Jensy
San Pedro Hospital
del Río Mayor, José Luis
San Pedro Hospital
Renal coloboma syndrome or papillorenal syndrome is an autosomal dominant genetic disorder characterized by congenital renal and ocular disorders associated with variations in the PAX2 gene. In this case report, a 46-year-old gentleman presented for ocular examination in the setting of systemic hypertension. Past medical history included a kidney transplant due to renal failure. Fundus examination revealed bilateral optic nerve abnormalities with a large central excavation, with numerous vessels radiating from the periphery of the optic disc, consistent with the Morning Glory anomaly. Optical coherence tomography (OCT) disclosed substantial thinning of retinal nerve fiber layer. Genetic studies revealed the heterozygous variant c.398delC in the 3’ exon of PAX2 gene not previously described in the peer-reviewed medical literature (searched using MEDLINE and cross-referenced literature).
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-11-16 18:22:44
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http://eyereports.org/index.php/eyereports/article/view/101
Eye Reports; Vol. 7 No. 1 (2020)
eng
Copyright (c)
oai:eyereports.org:article/102
2020-11-17T02:56:42Z
eyereports:ORIG
nmb a2200000Iu 4500
"201116 2020 eng "
2039-4756
2039-4748
10.16964/er.v7i1.102
doi
dc
Bird pecking ocular injury caused by a native Malayan bird
Krishna, Logeswari
Ophthalmology Department, University Malaya Eye Research Centre, University of Malaya, Kuala Lumpur, Malaysia.
Zakaria, Nor Aisyah
Ophthalmology Department, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia
Singh, Sujaya
Ophthalmology Department, University Malaya Eye Research Centre, University of Malaya, Kuala Lumpur, Malaysia
Choo, May May
Ophthalmology Department, University Malaya Eye Research Centre, University of Malaya, Kuala Lumpur, Malaysia
Lott, Pooi Wah
Ophthalmology Department, University Malaya Eye Research Centre, University of Malaya, Kuala Lumpur, Malaysia
Eye injuries resulting from bird pecking are rare but may cause permanent blindness. We report a case of penetrating ocular injury following a peck by a white-breasted waterhen. A 13-year-old girl presented with painful visual loss in her left eye after being pecked by her pet bird. She sustained a central corneal laceration and traumatic cataract in her left eye. Primary closure of corneal laceration was performed without complication. Broad spectrum topical and intravenous antibiotics were administered. After two weeks, she developed a mature white cataract. Subsequently, she underwent lens aspiration with intraocular lens implantation. Her vision improved drastically from 20/2400 to 20/60. Precautions should be taken while handling birds, especially when children are handling birds, in order to prevent any ocular injury. Parents play a vital role in preventing their child from getting injured by birds.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-11-16 18:22:44
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http://eyereports.org/index.php/eyereports/article/view/102
Eye Reports; Vol. 7 No. 1 (2020)
eng
Copyright (c)
oai:eyereports.org:article/104
2020-11-17T02:47:17Z
eyereports:ORIG
nmb a2200000Iu 4500
"201116 2020 eng "
2039-4756
2039-4748
10.16964/er.v7i1.104
doi
dc
Correlation of the cholesterol-to-high-density-lipoprotein Castelli risk index-1 with the choroidal and retinal nerve fiber layer thickness in patients with diabetes mellitus without retinopathy
Ercan, Zeynep Eylul
Hitit University Corum Education and Training Hospital
Purpose: To determine the choroidal thickness and retinal nerve layer (RNFL) thickness changes in patients with diabetes mellitus (DM) without retinopathy in relation to their glycated hemoglobin (HbA1c) and Castelli risk index-1 (CRI-1) levels.
Method: This study examined the right eyes of 340 subjects. CRI-1 was calculated as the total cholesterol divided by high-density lipoprotein cholesterol. Five groups of 68 eyes were defined as follows: Group 1, control group consisting of healthy subjects; Group 2, DM patients with HbA1c from 7% to 9%; Group 3, DM patients with HbA1c from 7% to 9% and CRI-1 greater than 4; Group 4, DM patients with HbA1c greater than 9.1%; and, Group 5, DM patients with HbA1c greater than 9.1% and with CRI-1 greater than 4. Optical coherence tomography (OCT) measurements were taken using enhanced depth imaging. Choroidal thickness (CT) and RNFL thickness were compared within groups.
Results: CT was found to be lower in all DM groups compared with healthy subjects. In all nasal areas, CT was significantly thinner in group 5 than group 4. RNFL loss was only seen in the inferior temporal quadrant of all DM patients compared with the control group. There was no statistically significant difference between subgroups in RNFL measurements.
Conclusion: CRI-1, which is a marker of combined dyslipidemia abnormalities, is in use to predict atherosclerotic changes in DM patients. This study determined the CRI-1 also correlates with the CT of diabetic eyes but not the RNFL, and it can be used as an additional criterion in ophthalmological follow-ups of diabetic patients.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-11-16 18:22:44
application/pdf
image/jpeg
image/jpeg
http://eyereports.org/index.php/eyereports/article/view/104
Eye Reports; Vol. 7 No. 1 (2020)
eng
Copyright (c)
oai:eyereports.org:article/106
2020-11-17T02:47:17Z
eyereports:ORIG
nmb a2200000Iu 4500
"201116 2020 eng "
2039-4756
2039-4748
10.16964/er.v7i1.106
doi
dc
Primary ocular sporotrichosis with granulomatous conjunctivitis
Lee, Hsin Yi
Universiti Malaya Eye Research Centre, Department of Ophthalmology, University Malaya
Ramli, Norlina
Universiti Malaya Eye Research Centre, Department of Ophthalmology, University Malaya, Kuala Lumpur, Malaysia
Govindasamy, Gayathri
Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Tham, Joon Hi
Department of Pathology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Goh, Siew Yuen
3. Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Sporotrichosis is an infection which is caused by the dimorphic fungus Sporothrix schenckii. Primary ocular sporotrichosis is uncommon in non-endemic areas and may be easily misdiagnosed, leading to a delay in initiation of treatment. In this case report, a 15-year-old girl, who is a post renal transplant patient presented with left eye swelling and localized redness at the medial canthal region. She was initially treated with topical antibiotics but there was no improvement. The addition of topical steroids led to the development of multiple nodules with central ulceration. Examination of the left eye showed granulomatous conjunctivitis. The features were suggestive of sporotrichosis and she was empirically started on oral itraconazole. A biopsy of the lesion showed caseating granulomatous inflammation and fungal PCR tested positive for Sporothrix schenckii. Her symptoms and clinical findings completely resolved after 3 weeks on itraconazole; however, her liver function deteriorated, and patient opted to discontinue the medication.
Ophthoscience Publishers, Baltimore, Maryland, USA
2020-11-16 18:22:44
application/pdf
http://eyereports.org/index.php/eyereports/article/view/106
Eye Reports; Vol. 7 No. 1 (2020)
eng
Copyright (c)
oai:www.eyereports.org:article/107
2020-11-17T03:06:39Z
eyereports:CASE